Research on the correlation between blood lead and red blood cell with reticulocyte multiple parameters in children

【Objective】To investigate the correlation between red blood cell,reticulocyte multiple parameters and blood lead in children. 【Methods】Blood lead levels were tested by atomic absorption spectrographic method.Blood cell and reticulocyte parameters were measured by automated hematology analyzer Sysmex XE-2000 in healthy and lead poisoning children. 【Results】In slight lead poisoning group,reticululocyte(RET),High fluorescence reticululocyte(HFR),middle fluorescence reticululocyte(MFR) were higher than those in healthy group(P0.01),low fluorescence reticululocyte(LFR) was lower than that in normal group(P0.01),There was no significaut difference in erythrocyte(RBC),hemoglobin(HGB),hematocrit(HCT),mean corpuscular volume(MCV),mean corpuscular hemoglobin(MCH) and mean corpuscular hemoglobin concentration(MCHC).There was significant difference in RBC,HGB,HCT and RET,RIF,HFR,MFR,LFR between moderate lead poisming group and healthy group. 【Conclusions】Reticulocyte parameters can reflect the lead poisoning earlier than RBC parameters.Reticulocyte parameters has important clinical value in diagnosing children's lead poisoning.