Abstract 2632: Calmodulin Kinase Inhibition Prevents the Arrhythmogenesis in Ryr2r4496c+/− Knock in Mice

Nian Liu,Yanfei Ruan,Marco Denegri,Bachetti Tiziana,Yang Li,Barbara Colombi,Carlo Napolitano,William A. Coetzee,Silvia G. Priori

Circulation（2009）

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摘要

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is caused by mutations in the cardiac ryanodine receptor gene (RyR2) leading to life-threatening arrhythmias elicited by sympathetic act...

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