Observation on the clinical efficacies of different therapies for asthmatic suffocating bronchopneumonia

Objective:To observe the clinical efficacies of different therapies for asthmatic suffocating bronchopneumonia(ASP).Methods:One hundred and twenty children with ASP were divided into conventional therapy group,systematic hormone therapy group,hormone atomization inhalation therapy group,and vitamin K1 therapy group randomly.The children in conventional therapy group were treated with symptomatic treatment,such as anti-infection,stopping cough,and eliminating phlegm;on the basis of conventional therapy,the children in systematic hormone therapy group were treated with intravenous drip of succinate hydrocortisone(50 mg/kg) for successive five days;the children in hormone atomization inhalation therapy group were treated with atomization inhalation of budesonide(0.5 mg),twice a day for successive five days;the children in vitamin K1 therapy group were treated with vitamin K1,0.3-0.5 mg/kg per time,twice a day for successive five days.The clinical efficacies and adverse reactions were observed.Results:After treatment,symptom scores in the four groups increased significantly,compared with conventional therapy group,the improvements of symptoms in the other three groups were more obvious(P0.05).The obvious effective rate,effective rate,ineffective rate,and total effective rate in systematic hormone therapy group were 69%,21%,10% and 90%,respectively;the obvious effective rate,effective rate,ineffective rate,and total effective rate in hormone atomization inhalation therapy group were 72%,19%,9%,and 91%,respectively;the obvious effective rate,effective rate,ineffective rate,and total effective rate in vitamin K1 therapy group were 57%,29%,14%,and 86%,respectively.The obvious effective rate,effective rate,ineffective rate,and total effective rate in the above-mentioned three groups were all significantly higher than those in conventional therapy group(obvious effective rate(32%),effective rate(29%),ineffective rate(39%),and total effective rate(61%))(P0.05).Conclusion:The curative effects of systematic hormone therapy and hormone atomization inhalation therapy were dominant,the curative effect of vitamin K1 therapy was similar to that of hormone therapy.For the children with ASP who reject hormone therapy or can't be treated with hormone therapy,systematic use of vitamin K1 can be used a method to relieve asthma.