Microwave‐Assisted Organocatalytic Multicomponent Knoevenagel/Hetero Diels—Alder Reaction for the Synthesis of 2,3‐Dihydropyran[2,3‐c]pyrazoles.

Marco Radi,Vincenzo Bernardo,Beatrice Bechi,Daniele Castagnolo,Mafalda Pagano,Maurizio Botta

ChemInform（2010）

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摘要

Abstract A rapid protocol for the multicomponent microwave-assisted organocatalytic domino Knoevenagel/hetero Diels–Alder reaction (DKHDA) has been developed for the synthesis of 2,3-dihydropyran[2,3- c ]pyrazoles. The reported procedure could be used for the fast generation of novel substituted 2,3-dihydropyran[2,3- c ]pyrazoles with potential anti-tuberculosis activity.

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