Discovery of 7‐Arylsulfonyl‐1,2,3,4,4a,9a‐hexahydro‐benzo[4,5]furo[2,3‐c]pyridines: Identification of a Potent and Selective 5‐HT6 Receptor Antagonist (I) Showing Activity in Rat Social Recognition Test.
ChemInform（2012）
摘要
The key step in the synthesis of (I) is the CuI-mediated coupling reaction between methoxy-isopropyloxybenzenethiol and 7-iodo-hexahydro-benzofuropyridine followed by S-oxidation with MCPBA.
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