Pseudomonas aeruginosa quorum-sensing homoserine lactone inhibits O2 consumption and stimulates H+ secretion by airway epithelia (869.2)

P. aeruginosa biofilms accumulate in the airways of cystic fibrosis patients and produce the quorum-sensing molecule N-(3-oxododecanoyl)-homoserine lactone (C12) that depolarizes mitochondria. We t...