Lbos 01-01a comparison of the impact of morning or night delivery of antihypertensive agents on 24 hour abpm levels: a randomised cross-over trial (harmony).

Objective:Some data suggest that nocturnal rather than daytime dosing of antihypertensive agents may have beneficial effects on consequent cardiovascular outcomes. This trial was designed to evaluate whether ABPM levels differ by timing of drug dosing, as a possible explanation for these observation