Abstract 14086: Seattle Heart Failure Model Identifies Patients Most Likely to Have Improved Survival With Cardiac Resynchronization Therapy Defibrillators - An NCDR Analysis

Introduction: In the Sudden Cardiac Death in Heart Failure Trial, lower Seattle Heart Failure Model (SHFM) risk was associated with an increased survival benefit with implantable cardioverter defibrillators (ICDs), but the impact of SHFM risk on the survival benefit with cardiac resynchronization therapy defibrillators (CRT-D) remains to be determined. Hypothesis: Increasing SHFM risk will be associated with a greater impact of CRT-D on survival in the National Cardiovascular Data Registry (NCDR) ICD Registry. Methods: The study cohort consisted of patients with CRT-D from the NCDR ICD Registry with current criteria for CRT-D implantation. The control cohort consisted of patients from the University of Washington Registry, Italian Heart Failure Registry, Swedish Heart Failure Registry, COMET, Val-HeFT, and PRAISE trials who met standard criteria for CRT-D but who did not receive CRT-D. Multivariable logistic regression with receiver operating characteristic (ROC) analysis and multivariable Cox proportiona...