Longitudinal Impact of Sputum Inflammatory Phenotypes on Small Airway Dysfunction and Disease Outcomes in Asthma
The Journal of Allergy and Clinical Immunology: In Practice(2022)
摘要
In asthma, airway eosinophilic inflammation is the main driver of lung function impairment and poor disease outcomes, which might also be aggravated by the coexistence of airway neutrophilia to confer a severe mixed granulocytic asthma phenotype. Persistent airway eosinophilia might be associated with dynamic SAD even in patients with stable FEV1.
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关键词
Eosinophilic asthma,Mixed granulocytic asthma,Airway inflammation,Small airway dysfunction
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