Dosimetric impact of target definition in brachytherapy for cervical cancer – Computed tomography and trans rectal ultrasound versus magnetic resonance imaging

Physics and Imaging in Radiation Oncology(2022)

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摘要
•This study evaluated the dosimetric impact of target volume delineation in Computed Tomography (CT) with assistance from Trans Rectal Ultrasound (TRUS) as compared to Magnetic Resonance Imaging (MRI) image-based brachytherapy for cervical cancer.•No statistically significant systematic difference was found between MRI and CT for target structures.•However, considerable variations were seen on individual patient level which needs to be considered during clinical practice, which also needs further investigations.•Current findings provide useful information to optimally utilize various imaging modalities for brachytherapy planning.•Although, CT + TRUS based delineation of target volume, appear promising, MRI remains the gold standard.
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关键词
Computed Tomography,High risk Clinical target volume,Brachytherapy,Cervical cancer
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