Simultaneous diffuse optical and bioluminescence tomography to improve source localization

Alexander Bentley,Xiangkun Xu,Zijian Deng,Jonathan E. Rowe,Ken Kang-Hsin Wang,Hamid Dehghani

Diffuse Optical Spectroscopy and Imaging VIII（2021）

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摘要

A novel algorithm to simultaneously recover bioluminescence source location and optical parameters is developed. In-vivo studies show 30% improvement in localization error while also providing local total hemoglobin concentration.

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