Simulating the effect of cerebral blood flow changes on regional quantification of [18F]flutemetamol and [18F]florbetaben studies

Fiona Heeman,Maqsood Yaqub,Isadora Lopes Alves, Kerstin Heurling,Santiago Bullich,Juan Domingo Gispert,Ronald Boellaard,Adriaan A. Lammertsma

Journal of Cerebral Blood Flow and Metabolism（2021）

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摘要

Global and regional changes in cerebral blood flow (CBF) can result in biased quantitative estimates of amyloid load by PET imaging. Therefore, the current simulation study assessed effects of thes...

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cerebral blood flow changes,cerebral blood flow,regional quantification

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