Self-examination low-cost full-field OCT (SELFF-OCT) allows treatment decision for age related macular degeneration (AMD) and diabetic macular edema (DME) with high sensitivity and specificity: clinical pilot study
https://doi.org/10.1117/12.2583041(2021)
摘要
The treatment of macular diseases requires frequent monitoring by optical coherence tomography (OCT). Home monitoring would reduce the burden of frequent clinical visits and increase therapy adherence. In a pilot study with 47 patients having different macular diseases we tested a proprietary self-examination low-cost full-field OCT (SELFF-OCT). For comparison, scans with a standard clinical spectral domain OCT were taken. Data was graded by a reading center. Patients were able to successfully acquire images that were clinically gradable for 85% of the included eyes. The sensitivity and specificity for an anti-VEGF treatment decision based on the SELFF-OCT was 0.94 and 0.95, respectively.
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