Clinico-laboratory profile in children with status epilepticus and correlation to short-term outcomes at Sohag University Hospital

Background: Status Epilepticus is a major neurological and medical emergency. Despite the advance in treatment, it is still associated with mortality and morbidity. It is a common pediatric neurological emergency with an estimated incidence of 18–23 per 100,000 children per year and mortality of 2%–7%.Objective: The objectives of the study were to determine the clinical profile, immediate outcome and possible risk factors of SE in the pediatric age group admitted at Sohag University Hospital. Patients and Methods: In this research, we have studied 100 patients who were admitted to the pediatric department over a period of 1 year 56 were males and 44 were females, Their ages ranged from one month to 15 years with a mean age was 37.8±44.4 months and those patients were subjected to full clinical histories, clinical and laboratory examination.Results: In our study, we found that 38% of patients were improved without any neurological deficits. 15.8% of patients who had epileptic seizures were related significantly to improved outcomes, while recurrence outcome represents about 59.3% in those patients who presented with epilepsy. patients presented with hypoxic-ischemic encephalopathy show the highest mortality rate (38.1%) among the deaths(21%). Conclusion: In this study, we found that in the included children, epilepsy is the most common cause of status epilpticus and those epileptic children were significantly related to the improvement and recurrence outcome, patients presented with hypoxic-ischemic encephalopathy were significantly related to death outcome and all patients presented with status epilepticus should have full clinical examination and laboratory investigations.