Bacteriophage and its Potential for Therapeutic Use in Brucellosis among Cattles

Bacteriophages are viruses that can specifically kill certain bacteria. This property of phages can be exploited for therapeutic application in treating bacterial infections in domestic animals. Brucellosis is an important zoonotic disease which is endemic in several countries. Antibiotics are not very effective against bovine brucellosis and the cost of this treatment is very high. Lytic phages against Brucella have been isolated and have been tried for therapy of bovine brucellosis with encouraging results. The present study reviewed the studies on bacteriophages with special reference to Brucellaphage and their application in the therapy of bovine brucellosis.