Abstract 13414: Studying Sonoporation-Induced Drug Payload Penetration Beyond the Blood-Brain Barrier Using Multi-Cellular Human Brain Spheroids

Anurag N Paranjape,Leonardo D’Aiuto,Wenxiao Zheng,Thiruganesh Ramasamy,Xucai Chen,Flordeliza S. Villanueva

Circulation（2021）

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摘要

Introduction: Ultrasound-targeted microbubble cavitation (UTMC) facilitates delivery of cell-impermeant drugs across the endothelial barrier, such as the blood brain barrier (BBB). Using cultured e...

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