“Walking” into freely moving brain monitoring via real-time TD-NIRS

Thanks to recent developments in time-domain near-infrared spectroscopy (TD-NIRS), it is now possible to monitor brain activity during freely moving exercises. A wearable single-channel TD-NIRS instrument has been exploited to retrieve oxy- and deoxygenated hemoglobin absolute concentrations during gaiting experiments. It was possible to retrieve quantitative results concerning functional brain activation in the motor cortex areas, with high rejection of motion artifacts.