Genetic Variation in SLC5A2 Mimicking SGLT2-Inhibition Lowers Risk of Cardiovascular Disease and All-Cause Mortality

Louise E. Bechmann,Frida Emanuelsson,Borge G. Nordestgaard,Marianne Benn

Circulation（2021）

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摘要

Background: Treatment with sodium-glucose co-transporter 2 (SGLT2)-inhibitors reduces risk of hospitalization for heart failure and all-cause mortality, but the mechanisms are unclear. Hypothesis: ...

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