Durability of response to immune checkpoint inhibitors in metastatic Merkel cell carcinoma after treatment cessation.

Alison M Weppler,Laetitia Da Meda,Ines Pires da Silva,Wen Xu,Giovanni Grignani,Alexander M Menzies,Matteo S Carlino,Georgina V Long, Serigne N Lo,Ina Nordman,Christopher B Steer,Megan Lyle,Claudia Trojaniello,Paolo A Ascierto,Celeste Lebbe,Shahneen Sandhu

European journal of cancer (Oxford, England : 1990)（2023）

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摘要

ICI responses in mMCC do not appear durable off treatment, including in patients who achieve a CR, though response to retreatment is promising. Extended duration of treatment needs to be investigated to optimise long-term outcomes.

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关键词

Durability of response,Immune checkpoint inhibitors,Merkel cell carcinoma,Retreatment,Treatment cessation

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