Abstract 9512: Involvement of Orai1 Ca2+Channel in the Pathogenesis of Pulmonary Arterial Hypertension. Orai1 as a New Potential Therapeutic Target?

Bastien Masson,Hélène Le Ribeuz,Jessica Sabourin,Emily Woodhouse,Richard Foster, Yann Ruchon, Mary Dutheil,Angèle Boet,Maria-Rosa Ghigna,Olaf Mercier,David J. Beech,Jean-Pierre Benitah,Marc A. Bailey,Marc Humbert,David Montani,Véronique Capuano,Fabrice Antigny

Circulation（2021）

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摘要

Introduction: Pulmonary arterial hypertension (PAH) is a devastating disease, characterized by a progressive obstruction of distal pulmonary artery (PA) leading to right ventricular hypertrophy and...

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