Microwave assisted synthesis of phenanthridine derivatives via Suzuki coupling and condensation
Results in Chemistry(2021)
摘要
Abstract One-pot synthesis of phenanthridine derivatives using appropriately substituted aromatic ortho-bromo N-tosylhydrazones and 2′-aminobenzeneboronic acid pinacol esters is described. In the presence of Pd(amphos)Cl2 catalyst, tosylhydrazone precursors undergo a Suzuki cross-coupling reaction with 2′-aminobenzeneboronic acid pinacol ester derivatives followed by intramolecular condensation to form the corresponding phenanthridines derivatives in one step.
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关键词
Phenanthridines,Tosylhydrazones,2 '-aminophenylboronic acid pinacol esters,Suzuki coupling,Condensation reaction,One pot synthesis
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