Chemical constituents ofImpatiens chapaensis Tard. and theirα-glucosidase inhibition activities

Natural Product Research(2021)

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摘要
Sixteen compounds (1-16) were isolated from Impatiens chapaensis. Chemical structures were determined by spectroscopic analyses and comparisons with previously published data. This report is the first to identify compounds 1, 5-7, 10, 12-14, and 16 from the genus Impatiens. Seven chosen isolates (5, 7, 10, 11, 12, 15, and 16) were submitted for α-glucosidase inhibition assays with acarbose as the positive control (IC50 = 227.14 ± 13.71 µM). Flavonoid 5 exhibited a significant inhibitory effect (IC50 = 101.00 ± 9.01 µM).
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关键词
Impatiens chapaensis,Balsaminaceae,flavonoid glycoside,sesquiterpene,neolignan glycoside
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