A particular photodynamic therapy for the treatment of refractory spontaneous maxillary onj: a case report

Drug-related osteonecrosis of the jaw (MRONJ) is a drug complication characterized by the progressive destruction and necrosis of the bone, in the absence of previous radiation treatment. In the present report, a 58-year-old cancer patient treated with zolendronic acid developed a spontaneous palatal osteonecrosis. Following repeated courses of antibiotic therapy, there was no improvement of the osteonecrosis. Subsequently, after several attempts, an integrum healing occurred with the use of an 810 nm diode laser at 3.5 W and 10% povidone iodine as photosensitizer, with the addition of 0.330 g of acetylsalicylic acid. and 0.200 g of vitamin C as a final rinse. Therefore, the aim of our work is to illustrate the resolution of a spontaneous maxillary ONJ with this particular PDT.