IRX5 Transcription Factor Cooperate With TBX5/GATA4/NKX2-5 Complex to Regulate Several Human Cardiomyocyte Functions

Robin Canac,Bastien Cimarosti, Aurore Girardeau,Virginie Forest,Cynthia Fourgeux,Jeremie Poschmann,Guillaume Lamirault,Patricia Lemarchand,Nathalie Gaborit

Circulation（2021）

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摘要

Introduction: The transcription factor (TF) Iroquois homeobox 5 (Irx5) is a key patterning and differentiation regulator. In humans, IRX5 regulates the expression of the main cardiac sodium ion cha...

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