In Vivo Function of Flow-Responsive Cis -DNA Elements of the Endothelial Nitric Oxide Synthase Gene: A Role for Chromatin-Based Mechanisms.

Kyung Ha Ku,Michelle K. Dubinsky,Aravin N. Sukumar,Noeline Subramaniam,Manon Y M Feasson,Ranju Nair,Eileen Tran,Brent M. Steer,Britta J. Knight,Philip A. Marsden

Circulation（2021）

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摘要

Background: eNOS (endothelial nitric oxide synthase) is an endothelial cell (EC)–specific gene predominantly expressed in medium- to large-sized arteries where ECs experience atheroprotective lamin...

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