Abstract 13147: The Internally Translated Isoform of Connexin 43, GJA1-20k Rescues Cx43 Trafficking and Reduces Arrhythmias in the DSG2 Mutant Model of Arrhythmogenic Cardiomyopathy

Joseph A. Palatinus,Steven Valdez,Claire Whisenant,André G. Kléber, Jeffrey E. Saffitz,Robin M. Shaw

Circulation(2021)

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摘要
Introduction: Arrhythmogenic cardiomyopathy (ACM) is an inherited condition caused by mutations of junctional proteins resulting in heart rhythm abnormalities, heart failure and sudden cardiac deat...
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