Direct on-sensor imaging for shadow-based microparticle characterization and bioluminescence imaging (Conference Presentation)

Here we describe a lens free on-sensor imaging platform which is able to perform a high spatial resolution imaging over the large field of view. By measuring the geometrical shadow of the microscopic objects at different oblique illumination angles, we were able to measure the height of these objects. In addition, we were able to record bacterial bioluminescence signals directly on the CMOS chip. This is, to our knowledge, the first report of lens-less, on-sensor bioluminescence measurements.