IL-4Ra-Mediated CD206(+) Macrophage Activation Promotes Adverse Remodeling in the Failing Heart

Qiongxin Wang,Mohamed Ameen Ismahil,Gregg Rokosh,Yujie Zhu,Tariq Hamid,Sumanth Prabhu

Circulation（2021）

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Background: In heart failure (HF), cardiac macrophages are largely comprised of CD206+ cells that locally self-renew independent of the blood monocyte pool. We tested the hypothesis that cardiac CD...

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Cardiac Remodeling

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