Type 1 Diabetes Alters Estrogen-Stimulated microRNA Expression and Impairs Nitric Oxide Production in Human Coronary Artery Endothelial Cells

Jingli Wang, Benjamin Hofeld,Venkata K. Puppala,Rong Ying,Ryan A. Harris,Michael E. Widlansky

CIRCULATION（2021）

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摘要

Introduction: Women developed CAD about 1 decade after men. This advantage is erased in T1DM women, and the mechanisms remain unclear. Estrogen (E2) stimulates endothelial NO production via estroge...

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