Loneliness as Risk Factor for Alzheimer´s disease.

Current aging science(2022)

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摘要
There is considerable empirical evidence that unequivocally points to loneliness as a modifiable risk factor for the development of Alzheimer's disease and other related dementias. With the emergence of the COVID-19 pandemic and the resulting lockdown and social distancing, there has been a renewed interest in studying this topic. The present review examines the links between loneliness and Alzheimer's disease, with particular emphasis on the mechanisms common to both conditions.
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关键词
Alzheimer disease,Dementia,amygdala,cronic stress,hippocampus,social behavior
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