Systematic comparison between BNT162b2 and CoronaVac in the seroprotection against SARS-CoV-2 Alpha, Beta, Gamma, and Delta variants

Wing Ying Au,Chengjin Ye, Sydney Leigh Briner,Gianmarco Domenico Suarez, Jeewon Han,Xinzhou Xu,Jun-Gyu Park,Melinda Ann Brindley,Luis Martinez-Sobrido,Peter Pak-Hang Cheung

Journal of Infection（2022）

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摘要

•Sera from BNT162b2 recipients seroprotects more than Coronavac.•While BNT162b2 seroprotect Beta less, Coronavac protects against all variants similarly to original WA1 strain.•Antibodies elicited by Cornavac can bind to both Spike and Nucleocapsid, whereas BNT162b2 could only bind to spike.

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