Safety of gadolinium based contrast agents in magnetic resonance imaging-guided radiotherapy – An investigation of chelate stability using relaxometry

Physics and Imaging in Radiation Oncology(2022)

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摘要
•No change in Gd-chelate relaxation rate after irradiation with high-energy X-rays.•Complete breakage of Gd-chelate by high-energy X-rays not detected.•In-vitro, complete breakage of Gd-chelate is below clinically relevant level.
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关键词
Gadolinium based contrast agent,Magnetic resonance imaging,Radiotherapy,Safety,Toxicity,NMR relaxometry
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