Orthostatic changes in blood pressure and survival in elderly cardiopaths

Laura Mariana de Siqueira Mendonça Chaves,João Victor Batista Cabral,Maria Mariana Barros Melo da Silveira, Márcia Cristina Amélia da Silva, Analú Corrêa de Souza,Dinaldo Cavalcanti de Oliveira,Dário Celestino Sobral Filho,Ulisses Ramos Montarroyos

REVISTA DA ASSOCIACAO MEDICA BRASILEIRA(2022)

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摘要
OBJECTIVE: The objective of this study was to analyze the association between orthostatic changes in blood pressure and mortality in elderly cardiopath patients. METHODS: A cohort of 455 elderly cardiopath patients, monitored at a referral outpatient cardiology clinic in Pernambuco, Brazil, from October 2015 to July 2018. The exposure groups were formed according to their orthostatic changes in blood pressure following the requirements of the Brazilian Guidelines for Hypertension. RESULTS: Orthostatic hypotension was present in 46 patients (10.1%), 91 had orthostatic hypertension (20%), and 318 had no orthostatic alterations (69.9%). There were 52 deaths duringfollow-up. The results demonstrated that there was no statistically significant association between orthostatic hypotension and overall mortality (HR 1.30; 95%CI 0.53-3.14; p=0.567) nor between orthostatic hypertension and overall mortality (HR 0.95; 95%CI 0.65-1.39; p=0.34). Survival in relation to the exposure groups presented no statistically significant difference (p=0.504). CONCLUSION: There was a low frequency of orthostatic hypotension and a mild high frequency of orthostatic hypertension when compared with previous studies, and no association was observed with overall mortality or with the survival time of elderly patients with heart disease.
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关键词
Orthostatic hypotension, Hypertension, Mortality
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