Genetically diverse mouse models of SARS-CoV-2 infection reproduce clinical variation and cytokine responses in COVID-19.

Shelly J Robertson,Olivia Bedard,Kristin L McNally,Matthew Lewis,Chad Clancy,Carl Shaia,Rebecca M Broeckel,Abhilash I Chiramel,Gail L Sturdevant,Elvira Forte,Christoph Preuss, Candice N Baker, Jeffrey Harder,Catherine Brunton,Steven Munger,Daniel E Sturdevant,Craig Martens,Steven M Holland,Nadia A Rosenthal,Sonja M Best

bioRxiv : the preprint server for biology（2022）

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摘要

Genetically diverse mice display a broad spectrum of clinically relevant responses to SARS-CoV-2 infection, reflecting variability in COVID-19 disease.

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