Twice Daily Compared to Three Times Daily Hydrocortisone in Prepubertal Children with Congenital Adrenal Hyperplasia.

Jennifer Apsan,Charlene Thomas,Hailan Elnaas,Karen Lin-Su,Oksana Lekarev

Hormone research in paediatrics（2022）

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摘要

BID dosing provides similar adrenal control and does not appear to impact growth or bone age advancement. On the other hand, TID dosing does not appear to increase the metabolic side effect profile in this age-group. Dosing should be patient-centered with individualized consideration.

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关键词

Congenital adrenal hyperplasia,Glucocorticoids,Metabolic impacts,Prepubertal growth

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