Arginase is involved in cervical lesions progression and severity

Moufida Souid,Randa Ghedira,Sameh Souissi, Nadia Bouzgarrou,Sallouha Gabbouj, Salwa Shini-Hadhri, Mohamed-Saleh Rhim, Asma Boukadida,Dhekra Toumi,Raja Faleh,Noureddine Bouaouina, Abdelfatteh Zakhama,Elham Hassen

Immunobiology（2022）

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摘要

•Arginase activity and mRNA expression are associated with cervical lesions.•Arginase activity is inversely correlated to anti-HPV16 IgG in cervical lesions.•Arginase activity and mRNA expression are correlated to HPV16 in cervical lesions.•ARG2 could be a promising target to cervical cancer therapy.

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关键词

ASCUS,CI,CIN,ELISA,GST,HPV,HSIL,IDO,ISPF,IQR,LSIL,MDSC,NILM,OD,OR,PBS,SCC,TMB,TAM

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