Combination Therapies with Ablation: Immunoablation
Digestive Disease Interventions(2020)
摘要
AbstractPercutaneous ablation has been increasingly utilized as an alternative or adjunct to surgical resection of solid tumors. However, high rates of local recurrence and disease progression both with resection and ablation, particularly in patients with primary and metastatic liver malignancies, have limited further extension of overall survival. Systemic oncology treatment has progressed beyond traditional chemotherapeutic agents to immunotherapeutic agents that exert their effect by enhancing the body's immune response against cancer cells. The induction of necrotic cell death and the release of a large number of tumor antigens as a result of ablation have stimulated interest in combination therapy as a potential method of improving response to immunotherapy. This review focuses on the current scientific evidence for combination therapy of immuno-oncologic agents and locoregional ablation techniques.
更多查看译文
关键词
ablation,therapies
AI 理解论文
溯源树
样例
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要