G_qα/G₁₁α deficiency in dorsomedial hypothalamus leads to obesity resulting from decreased energy expenditure and impaired sympathetic nerve activity

Eric A. Wilson,Hui Sun,Zhenzhong Cui, Marshal T. Jahnke, Mritunjay Pandey,Peter Metzger,Oksana Gavrilova,Min Chen,Lee S. Weinstein

American Journal of Physiology-Endocrinology and Metabolism（2021）

引用 0|浏览0

暂无评分

摘要

This paper demonstrates that signaling within the dorsomedial hypothalamus via the G proteins Gqα and G11α, which couple cell surface receptors to the stimulation of phospholipase C, is critical for regulation of energy expenditure, thermoregulation by brown adipose tissue and the induction of white adipose tissue browning.

查看译文

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要

Gqα/G11α deficiency in dorsomedial hypothalamus leads to obesity resulting from decreased energy expenditure and impaired sympathetic nerve activity

G_qα/G₁₁α deficiency in dorsomedial hypothalamus leads to obesity resulting from decreased energy expenditure and impaired sympathetic nerve activity