Multi-scale models of the heart for patient-specific simulations

This chapter presents a general overview on computational models of the heart. It focuses on mathematical modeling of the various physiological aspects involved in cardiac function, namely anatomy, electrophysiology, biomechanics, fluid dynamics and fluid structure interaction. Their implementation is described in the next chapter. The goal of this chapter is to give a brief introduction of each physiological system, and examples of mathematical models that have been developed so far by the community, along with their advantages and potential limitations in view of patient-specific simulations.