Design of Bimodal Ligands of Neurotensin Receptor 1 for Positron Emission Tomography Imaging and Fluorescence-Guided Surgery of Pancreatic Cancer

Emma Renard, Pierre-Alix Dancer,Christophe Portal,Franck Denat,Aurélie Prignon,Victor Goncalves

Journal of Medicinal Chemistry（2019）

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摘要

Neurotensin receptor 1 (NTSR1) is overexpressed in most human pancreatic ductal adenocarcinomas. It makes it an attractive target for the development of pancreatic cancer imaging agents. In this st...

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