Organocatalytic asymmetric synthesis of both cis- and trans-configured pyrano[2,3-b]chromenes via different dehydration pathways

Organic Chemistry Frontiers(2019)

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摘要
The enamine-catalyzed [3 + 3]-cycloaddition between chroman-2-ols and β,γ-unsaturated α-ketoesters is developed to access both enantiomers of cis- and trans-fused pyrano[2,3-b]chromene derivatives.
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