Design, synthesis, and in vitro and in vivo characterization of 1-{4-[4-(substituted)piperazin-1-yl]butyl}guanidines and their piperidine analogues as histamine H₃ receptor antagonists

MedChemComm（2019）

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摘要

The prominent members of 1-{4-[4-(substituted)piperazin-1-yl]butyl}guanidines as histamine H3 receptor antagonists.

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Design, synthesis, and in vitro and in vivo characterization of 1-{4-[4-(substituted)piperazin-1-yl]butyl}guanidines and their piperidine analogues as histamine H3 receptor antagonists