SIOPEL 6: A multicenter open-label randomized phase III trial of the efficacy of sodium thiosulphate (STS) in reducing ototoxicity in patients receiving cisplatin (Cis) monotherapy for standard-risk hepatoblastoma (SR-HB).

Rudolf Maibach,Margaret Childs,Kaukab Rajput,Edward A. Neuwelt,Derek Roebuck,Michael James Sullivan,Veronique Laithier,Milind Ronghe, Liane Lockwood, Patrizia dall'Igna,Eiso Hiyama,Benedicte Brichard,Jane Skeen, Maria Elena Mateos Gonzales,Monique Fabre,Giorgio Perilongo,Piotr Czauderna,Bruce Morland,Penelope Brock

Journal of Clinical Oncology（2014）

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摘要

TPS10094 Background: The SIOPEL 3 trial of Cis monotherapy and surgery in SR-HB showed a 3yr OS of 95% at 5 years. SR-HB is defined as tumor extension limited to PRETEXT I, II or III, no involvemen...

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