The transfer of multigene panel testing for hereditary breast and ovarian cancer to healthcare: What are the implications for the management of patients and families?

Sarab Lizard, Marie Eliade,Jeremy Skrzypski, Amandine Baurand, Caroline Jacquot, Geoffrey Bertolone,Catherine Loustalot,Charles Coutant,France Guy,Pierre Fumoleau,Yannis Duffourd,Laurent Arnould,Marie-Martine Padeano,Come Lepage,Sandy Chevrier,Frédérique Végran,Nicolas Sevenet,Francois Ghiringhelli,Romain Boidot,Laurence Faivre

Journal of Clinical Oncology（2016）

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摘要

e13116Background: Until recently, the molecular diagnosis of hereditary breast and ovarian cancer (HBOC) was mostly based on BRCA1 and 2 testing. The advent of next generation sequencing technologi...

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