Patient (pt)-reported function and symptoms in APHINITY: A randomized comparison of chemotherapy (C) + trastuzumab (H) + placebo (Pla) versus C + H + pertuzumab (P) as adjuvant therapy in pts with HER2-positive early breast cancer (EBC).

Jose Baselga, Jennifer A. Petersen, Emma Clark, Claire Barton,Eleonora Restuccia, Marion Jennifer Procter,Amir Sonnenblick, Debora Fumagalli, Damian Parlier, Amal Arahmani,Giuseppe Viale, Linda L. Reaby,Elizabeth Frank,Richard D. Gelber,Martine J. Piccart-Gebhart,Jose Bines, Gunter von Minckwitz, Sabina McGarrahan Gasper

Journal of Clinical Oncology（2018）

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521Background: In APHINITY (NCT01358877), adding P to H + C significantly improved invasive disease-free survival in pts with HER2-positive EBC (von Minckwitz, NEJM 2017). Pt-reported health-relate...

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