A light-driven dual-nanotransformer with deep tumor penetration for efficient chemo-immunotherapy.

Jiahui Peng,Fangman Chen,Yulu Liu,Fan Zhang,Lei Cao,Qiannan You,Dian Yang,Zhimin Chang,Mingfeng Ge,Li Li,Zheng Wang,Qian Mei,Dan Shao,Meiwan Chen,Wen-Fei Dong

Theranostics（2022）

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摘要

Designing a transformable nanosystem with improved tumor accumulation and penetration by tuning multiple physicochemical properties remains a challenge. Here, a near-infrared (NIR) light-driven nanosystem with size and charge dual-transformation for deep tumor penetration is developed. Methods:Results:in vitroin vivoConclusions:

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关键词

immunotherapy,light response,mesoporous organosilica nanoparticles,phototherapy,tumor penetration

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