Maternal Perfluorinated Compound Exposure and Risk of Early Pregnancy Loss: A Nested Case-control Study
Biomedical and Environmental Sciences(2022)
摘要
Early pregnancy loss,defined as a nonviable intrauterine pregnancy occurring before 12 weeks of gestation,is estimated to affect 25%of clinically diagnosed pregnancies [1] .Several demographic,lifestyle,and environmental risk factors have been reported to associate with the risk of early pregnancy loss,yet the causes of most early pregnancy losses remain elusive;thus,further studies are needed.Perfluorinated compounds(PFCs) are a class of widespread environmental pollutants that can adversely affect human reproductive health.Humans are inevitably exposed to PFCs through diet,water,air and dust.A wealth of epidemiological and toxicological research using a variety of animal models has warned of the persistence,bioaccumulation,and toxicity of PFCs [2] .
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关键词
maternal perfluorinated compound exposure,early pregnancy loss,case-control
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