Effects of Oral Pirfenidone on Colon Anastomosis Healing and Adhesion Formation in Rats.

Shadya Betancourt-Vicencio, Manuel Rodrigo Prieto-Aldape,Andrea Socorro Alvarez-Villaseñor,Clotilde Fuentes-Orozco,Ana Olivia Cortes-Flores,Guadalupe Castillo-Cardiel, José Antonio Sánchez-Martínez,Emilio Alberto Reyes-Elizalde,Paola Guadalupe González-Hernández, José Gerardo Zamora-Inzunza, Victoria Amaranta Romero-Arredondo,José Francisco Barbosa-Camacho,Irma Valeria Brancaccio-Pérez,Bertha Georgina Guzmán-Ramírez,Alejandro González-Ojeda

European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes（2022）

引用 1|浏览4

暂无评分

摘要

Our results revealed favorable effects of PFD in this low-risk colon anastomosis model; for example, the bursting pressure was higher, and the macroscopic adhesions were soft and exhibited less inflammatory infiltration and higher collagen content in the PFD group than in the control group. The results showing that PFD treatment was associated with better healing of minor adhesions seem to be paradoxical because the therapeutic indications for this drug are directed at treating fibrosing diseases.

查看译文

关键词

colon anastomosis healing,oral pirfenidone,adhesion formation

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要