A unimolecular theranostic system with H₂O₂-specific response and AIE-activity for doxorubicin releasing and real-time tracking in living cells

Xiaoying Gao, Jie Cao,Yinuo Song,Xiao Shu,Jianzhao Liu,Jing Zhi Sun,Bin Liu,Ben Zhong Tang

RSC Advances（2018）

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摘要

A theranostic drug delivery system composed of tetraphenylethene (AIE-gen), benzyl-boronic ester (trigger) and doxorubicin (drug) was synthesized and its functions in cell imaging, drug delivery tracking, and therapeutic effect were evaluated.

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A unimolecular theranostic system with H2O2-specific response and AIE-activity for doxorubicin releasing and real-time tracking in living cells

A unimolecular theranostic system with H₂O₂-specific response and AIE-activity for doxorubicin releasing and real-time tracking in living cells