Trichomonacidal Activity of 3,3′-Diindolylmethane (DIM) Is Additive to Metronidazole (MTZ) In Vitro, Supporting Future Oral/Topical Use

Alexandra Ibáñez-Escribano, Leyre Pernaute Lau,Juan José Nogal-Ruiz,Alicia Gómez-Barrio,Jose Antonio Escario, Michael A. Zeligs

Proceedings of the 1st Molecules Medicinal Chemistry Symposium, Barcelona, Spain（2017）

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摘要

New, safe, well tolerated, and versatile anti-trichomonal agents for oral and topical use are needed to combat spreading resistance of Trichomonas vaginalis to metronidazole (MTZ). [...]

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